Publications

Wesseling, JF, Phan, S, Bushong, E, Siksou, L, Marty, S, Pérez-Otaño, I, and Ellisman, MH (2019) Sparse force-bearing bridges between synaptic vesicles. Brain Struct. Funct. 224(9):3263-3276. PMID: 31667576
Raja, MK, Preobraschenski, J, Del Olmo-Cabrera, S, Martínez -Turrillas, R, Jahn, R, Pérez-Otaño, I, and Wesseling, JF (2019) Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts. eLife 8, pii: e40744. PMID: 31090538
Pérez-Otaño I, Larsen RS, and Wesseling JF (2016) Emerging roles of GluN3A-containing NMDA receptors in the central nervous system. Nature Reviews Neuroscience 17:623-635. PMID: 27558536
Mahfooz K, Marco S, Martínez-Turrillas R, Raja MK, Pérez-Otaño I, and Wesseling JF (2016) GluN3A promotes NMDA spiking by enhancing synaptic transmission in Huntington’s disease models. Neurobiology of Disease 93:47-56. PMID: 27072890
Mahfooz K, Singh M, Renden R, and Wesseling JF (2016) A Well-Defined Readily Releasable Pool with Fixed Capacity for Storing Vesicles at Calyx of Held. PLoS Computational Biology 12: e1004855. PMID: 27035349
Wesseling, JF, and Pérez-Otaño, I (2015) Modulating GluN3A expression in Huntington ́s disease: A new NMDA receptor-based therapeutic approach? JAMA Neurology, 11, 46-51. PMID: 25686081
García-Pérez, E, Mahfooz, K, Covita, J, Zandueta, A, and Wesseling, JF (2015) Levetiracetam accelerates the induction of supply-rate depression in synaptic vesicle trafficking. Epilepsia, 56:535-545. PMID: 25684406
Marco, S, Giralt, A, Petrovic M, Pouladi, M, Torres-Peraza, J, Watanabe, M, Graham, RK, Hayden, MR, Wesseling, JF, Alberch, J, and Pérez-Otaño, I (2013) Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine, 19, 1030-1038. PMID: 23852340.
Chowdhury, D, Marco, S, Zandueta, A, Rao, Y, Haucke, V, Wesseling, JF, Tavalin, SJ, Pérez-Otaño, I (2013) Tyrosine phosphorylation regulates endocytosis and surface expression of GluN3A-containing NMDARs. Journal of Neuroscience. 33, 4151-4164. PMID: 23447623
Gabriel, T, García Pérez, E, Goñi, J, Martínez-Turrillas, R, Lo, DC, Pérez-Otaño, I, Wesseling, JF (2011) A New Kinetic Framework for Synaptic Vesicle Trafficking Tested in Synapsin Knockouts. Journal of Neuroscience, 31, 11563-11577. PMID: 21832187
Roberts, AC, Díez-García, J, Rodriguiz, RM, López, IP, Luján, R, Martínez-Turrillas, R, Picó, E, Henson, MA, Bernardo, DR, Jarrett, TM, Clendeninin, DJ, López-Mascaraque, L, Feng, G, Lo, DC, Wesseling, JF, Wetsel, WC, Philpot, BD, and Pérez-Otaño, I (2009). Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation. Neuron 63: 342-356. PMID: 19679074
García-Pérez, E, Lo, DC, and Wesseling JF (2008b). Kinetic isolation of a slowly recovering component of short-term depression during exhaustive use at excitatory hippocampal synapses. Journal of Neurophysiology 100: 781-795. PMID: 18579659
García-Pérez E and Wesseling JF (2008a). Augmentation controls the fast rebound from depression at a central synapse. Journal of Neurophysiology 99: 1770-1786. PMID: 18199812
Wesseling, JF and Lo, DC (2002). Limit on the role of activity in controlling the release-readysupply of synaptic vesicles. Journal of Neuroscience 22:9708-20. PMID: 12427826
Stevens, CF and Wesseling, JF (1999b). Identification of a novel process limiting the rate of synaptic vesicle cycling at hippocampal synapses. Neuron 24:1017-1028. PMID: 10624963
Stevens, CF and Wesseling, JF (1999a). Augmentation is a potentiation of the exocytotic process. Neuron 22: 139-146. PMID: 10027296
Stevens, CF and Wesseling, JF (1998). Activity dependent modulation of the rate at which vesicles become available for exocytosis. Neuron 21:415-424. PMID: 9728922